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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1921 1
1922 1
1926 1
1934 1
1936 2
1947 1
1948 1
1952 1
1956 1
1958 2
1961 1
1962 1
1963 2
1964 4
1965 2
1966 6
1967 1
1968 2
1969 3
1970 3
1971 3
1972 3
1973 3
1974 5
1975 38
1976 38
1977 35
1978 30
1979 53
1980 46
1981 66
1982 61
1983 70
1984 99
1985 81
1986 87
1987 81
1988 106
1989 104
1990 106
1991 109
1992 114
1993 132
1994 122
1995 169
1996 136
1997 149
1998 142
1999 150
2000 174
2001 169
2002 169
2003 161
2004 182
2005 222
2006 201
2007 225
2008 227
2009 229
2010 257
2011 259
2012 257
2013 280
2014 363
2015 279
2016 315
2017 269
2018 286
2019 312
2020 305
2021 379
2022 334
2023 341
2024 150

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8,103 results

Results by year

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Page 1
Alternative cleavage and polyadenylation in health and disease.
Gruber AJ, Zavolan M. Gruber AJ, et al. Nat Rev Genet. 2019 Oct;20(10):599-614. doi: 10.1038/s41576-019-0145-z. Epub 2019 Jul 2. Nat Rev Genet. 2019. PMID: 31267064 Review.
Most human genes have multiple sites at which RNA 3' end cleavage and polyadenylation can occur, enabling the expression of distinct transcript isoforms under different conditions. Novel methods to sequence RNA 3' ends have generated comprehensive catalogues of polyadenyla …
Most human genes have multiple sites at which RNA 3' end cleavage and polyadenylation can occur, enabling the expression of distinct transcr …
The risk profile of electronic nicotine delivery systems, compared to traditional cigarettes, on oral disease: a review.
Zhang Q, Wen C. Zhang Q, et al. Front Public Health. 2023 May 15;11:1146949. doi: 10.3389/fpubh.2023.1146949. eCollection 2023. Front Public Health. 2023. PMID: 37255760 Free PMC article. Review.
Though most oral symptoms experienced by ENDS users are relatively mild and temporary compared to traditional cigarettes, the dangers of ENDS still exist. However, further research with longer follow-up periods is required to establish the long-term safety of …
Though most oral symptoms experienced by ENDS users are relatively mild and temporary compared to traditional cigarettes, the dangers …
Making Ends Meet.
Griffin TC. Griffin TC. JAMA. 2024 Mar 12;331(10):827-828. doi: 10.1001/jama.2024.0546. JAMA. 2024. PMID: 38358759
In this narrative medicine essay, a second-year medical student describes how slipping into poverty starting with her father's myocardial infarction has cast a long shadow that persists even in medical school....
In this narrative medicine essay, a second-year medical student describes how slipping into poverty starting with her father's myocardial in …
Challenges in identifying mRNA transcript starts and ends from long-read sequencing data.
Calvo-Roitberg E, Daniels RF, Pai AA. Calvo-Roitberg E, et al. bioRxiv [Preprint]. 2023 Jul 27:2023.07.26.550536. doi: 10.1101/2023.07.26.550536. bioRxiv. 2023. PMID: 37546743 Free PMC article. Preprint.
Here, we systematically assess the variability and accuracy of mRNA terminal ends identified by LRS reads across multiple sequencing platforms. ...Thus, it is necessary to be cautious when selecting sequencing approaches and/or interpreting data from long-read RNA s …
Here, we systematically assess the variability and accuracy of mRNA terminal ends identified by LRS reads across multiple sequencing …
Long noncoding RNAs: Re-writing dogmas of RNA processing and stability.
Wilusz JE. Wilusz JE. Biochim Biophys Acta. 2016 Jan;1859(1):128-38. doi: 10.1016/j.bbagrm.2015.06.003. Epub 2015 Jun 11. Biochim Biophys Acta. 2016. PMID: 26073320 Free PMC article. Review.
Most of the human genome is transcribed, yielding a complex network of transcripts that includes tens of thousands of long noncoding RNAs. Many of these transcripts have a 5' cap and a poly(A) tail, yet some of the most abundant long noncoding RNAs are processed in …
Most of the human genome is transcribed, yielding a complex network of transcripts that includes tens of thousands of long noncoding …
The Diversity of Long Noncoding RNAs and Their Generation.
Wu H, Yang L, Chen LL. Wu H, et al. Trends Genet. 2017 Aug;33(8):540-552. doi: 10.1016/j.tig.2017.05.004. Epub 2017 Jun 16. Trends Genet. 2017. PMID: 28629949 Review.
Long noncoding RNAs (lncRNAs) are emerging as potential key regulators in gene expression networks and exhibit a surprising range of shapes and sizes. ...These lncRNAs can be processed by several mechanisms, including ribonuclease P (RNase P) cleavage to generate mature 3' …
Long noncoding RNAs (lncRNAs) are emerging as potential key regulators in gene expression networks and exhibit a surprising range of …
Electronic nicotine delivery systems (ENDS): A convenient means of smoking?
Sala M, Gotti C. Sala M, et al. Pharmacol Res. 2023 Sep;195:106885. doi: 10.1016/j.phrs.2023.106885. Epub 2023 Aug 25. Pharmacol Res. 2023. PMID: 37634554 Free article. Review.
This review begins by describing how cigarette smoking led to the development of ENDS as a means of combatting nicotine addiction. ENDS are usually categorised as belonging to one of only three main generations, but a fourth has been added in order to differentiate …
This review begins by describing how cigarette smoking led to the development of ENDS as a means of combatting nicotine addiction. …
Long noncoding RNAs with snoRNA ends.
Yin QF, Yang L, Zhang Y, Xiang JF, Wu YW, Carmichael GG, Chen LL. Yin QF, et al. Mol Cell. 2012 Oct 26;48(2):219-30. doi: 10.1016/j.molcel.2012.07.033. Epub 2012 Sep 6. Mol Cell. 2012. PMID: 22959273 Free article.
We describe the discovery of sno-lncRNAs, a class of nuclear-enriched intron-derived long noncoding RNAs (lncRNAs) that are processed on both ends by the snoRNA machinery. ...
We describe the discovery of sno-lncRNAs, a class of nuclear-enriched intron-derived long noncoding RNAs (lncRNAs) that are processed …
Shepherding DNA ends: Rif1 protects telomeres and chromosome breaks.
Fontana GA, Reinert JK, Thomä NH, Rass U. Fontana GA, et al. Microb Cell. 2018 May 17;5(7):327-343. doi: 10.15698/mic2018.07.639. Microb Cell. 2018. PMID: 29992129 Free PMC article. Review.
In eukaryotes, DNA ends at chromosomal termini are packaged into proteinaceous structures called telomeres. Telomeres protect chromosome ends from erosion, inadvertent activation of the cellular DNA damage response (DDR), and telomere fusion. ...
In eukaryotes, DNA ends at chromosomal termini are packaged into proteinaceous structures called telomeres. Telomeres protect chromos …
8,103 results